2024 SOT Meeting
On March 10-14, 2024, Michaela Hvizdak presented her research work on PFAS in a poster format.
HCV antiviral drugs have the potential to adversely perturb the maternal-fetal communication axis through inhibition of CYP3A7 DHEA-S oxidation
The hepatitis C virus (HCV) poses a great risk to pregnant people and their developing fetus, yet no HCV antiviral treatment guidelines have been established.… Read More »HCV antiviral drugs have the potential to adversely perturb the maternal-fetal communication axis through inhibition of CYP3A7 DHEA-S oxidation
HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation
Drug Metab Dispos. 2024 May 16;52(6):516-525. doi: 10.1124/dmd.123.001434. ABSTRACT The hepatitis C virus (HCV) poses a great risk to pregnant people and their developing fetus,… Read More »HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation
2023 Christmas Lampe lab lunch
The Lampe lab volunteered at the Food Bank of the Rockies and had lunch at North County.
Polymerization of Physisorbed Molecular Monolayers via Overhanging Alkynyl Chains: Characterization of Polymerization Kinetics and Monolayer Durability
Langmuir. 2023 Nov 21;39(46):16457-16471. doi: 10.1021/acs.langmuir.3c02277. Epub 2023 Nov 9. ABSTRACT Monolayers self-assembled by triphenyleneethynylene (TPE) compounds bearing two terminal alkynyl chains were polymerized by… Read More »Polymerization of Physisorbed Molecular Monolayers via Overhanging Alkynyl Chains: Characterization of Polymerization Kinetics and Monolayer Durability
Johns Hopkins University
On October 4th, 2023. Dr. Lampe presented a seminar in the Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore (https://www.hopkinsmedicine.org/pharmacology-molecular-sciences), entitled: “Cytochrome P450… Read More »Johns Hopkins University
Correction: Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate
J Biol Chem. 2023 Sep 30;299(10):105283. doi: 10.1016/j.jbc.2023.105283. Online ahead of print. NO ABSTRACT PMID:37783037 | DOI:10.1016/j.jbc.2023.105283
Rocky Mountain Discussion group
On September 29th, 2023. Dr. Lampe hosted the 2023 Annual Meeting of the Rocky Mountain Discussion group, with some fantastic speakers!
Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach
Idiosyncratic drug reactions (IDRs) in their most deleterious form can lead to serious medical complications and potentially fatal events. Nevirapine (NVP), still widely used in… Read More »Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach
Focus on Pharmacology
On September 25th, 2023. Dr. Lampe presented a talk at the ASPET Focus on Pharmacology series: Advances in Drug Metabolism, hosted by DMDD, entitled “CYP3A7’s… Read More »Focus on Pharmacology