Skip to content


Postdoctoral Fellow, Ph.D.

Dr. Brian Tooker is a post-doctoral research scientist currently working under the guidance of Dr. Jed Lampe at the University of Colorado, Anschutz Medical Campus. Dr. Tooker received his BS in Microbiology and MS in Animal Science, both from Michigan State University where he utilized molecular biology tools and genomics to answer questions about the host immune response to facultative intracellular bacteria. Dr. Tooker went on to run laboratories at Iowa State University and the University of Colorado where he built upon his previous big data training in genomics to gain a greater understanding of T cell responses to metals using proteomic tools. Recently, Dr. Tooker completed his PhD in Toxicology at the University of Colorado, Anschutz Medical Campus under Dr. Nichole Reisdorph where he investigated monocyte and monocyte derived macrophage responses to polycyclic aromatic hydrocarbons mixture exposures using both classical molecular biology tools as well as untargeted metabolomics. Currently, Dr. Tooker is investigating how P. aeruginosa cytochrome P450 metabolism may be leading to both bacterial growth and the perpetuation of opportunistic bacterial colonization through alterations in antibacterial drug efficacy, fatty acid metabolism, and cholesterol catabolism.




Comparing the effects of an exposure to a polycyclic aromatic hydrocarbon mixture versus individual polycyclic aromatic hydrocarbons during monocyte to macrophage differentiation: Mixture exposure results in altered immune metrics

Nutrimetabolomics reveals food-specific compounds in urine of adults consuming a DASH-style diet

CpG promoter methylation status is not a prognostic indicator of gene expression in beryllium challenge

Accelerator mass spectrometry detection of beryllium ions in the antigen processing and presentation pathway

SELDI-TOF derived serum biomarkers failed to differentiate between patients with beryllium sensitisation and patients with chronic beryllium disease

Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkers

Beryllium-induced TNF-alpha production is transcription-dependent in chronic beryllium disease

Structure of the bovine natural resistance associated macrophage protein (NRAMP 1) gene and identification of a novel polymorphism

Phagocytosis of M. paratuberculosis fails to activate expression of NADH dehydrogenase and nucleolin-related protein in bovine macrophages

Survival tactics of M. paratuberculosis in bovine macrophage cells