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Brian TOOKER

Postdoctoral Fellow, Ph.D.

Dr. Brian Tooker is a post-doctoral research scientist currently working under the guidance of Dr. Jed Lampe at the University of Colorado, Anschutz Medical Campus. Dr. Tooker received his BS in Microbiology and MS in Animal Science, both from Michigan State University where he utilized molecular biology tools and genomics to answer questions about the host immune response to facultative intracellular bacteria. Dr. Tooker went on to run laboratories at Iowa State University and the University of Colorado where he built upon his previous big data training in genomics to gain a greater understanding of T cell responses to metals using proteomic tools. Recently, Dr. Tooker completed his PhD in Toxicology at the University of Colorado, Anschutz Medical Campus under Dr. Nichole Reisdorph where he investigated monocyte and monocyte derived macrophage responses to polycyclic aromatic hydrocarbons mixture exposures using both classical molecular biology tools as well as untargeted metabolomics. Currently, Dr. Tooker is investigating how P. aeruginosa cytochrome P450 metabolism may be leading to both bacterial growth and the perpetuation of opportunistic bacterial colonization through alterations in antibacterial drug efficacy, fatty acid metabolism, and cholesterol catabolism.

Brian