Drug Metab Dispos. 2025 Dec;53(12):100188. doi: 10.1016/j.dmd.2025.100188. Epub 2025 Oct 22. ABSTRACT The drug discovery and development process faces significant challenges, including high attrition rates… Read More »Novel emerging cell and organoid systems for the study of drug metabolism and toxicity in humans
Langmuir. 2023 Nov 21;39(46):16457-16471. doi: 10.1021/acs.langmuir.3c02277. Epub 2023 Nov 9. ABSTRACT Monolayers self-assembled by triphenyleneethynylene (TPE) compounds bearing two terminal alkynyl chains were polymerized by… Read More »Polymerization of Physisorbed Molecular Monolayers via Overhanging Alkynyl Chains: Characterization of Polymerization Kinetics and Monolayer Durability
Biosynthetic methods have the potential to deliver value-added chemicals from renewable feedstocks. However, despite major advances in metabolic engineering and synthetic biology, the rapid engineering… Read More »Merger of Whole Cell Biocatalysis with Organocatalysis Upgrades Alcohol Feedstocks in a Mild, Aqueous, One-Pot Process